QX-314 chloride

CAS No. 5369-03-9

QX-314 chloride ( —— )

Catalog No. M24522 CAS No. 5369-03-9

QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 43 In Stock
50MG 74 In Stock
100MG 119 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    QX-314 chloride
  • Note
    Research use only, not for human use.
  • Brief Description
    QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
  • Description
    QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    sodium channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5369-03-9
  • Formula Weight
    298.9
  • Molecular Formula
    C16H27ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:14.29 mg/mL (47.82 mM; Need ultrasonic)
  • SMILES
    O=C(NC1=C(C)C=CC=C1C)C[N+](CC)(CC)CC.[Cl-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology. 2011 Jun;114(6):1425-34.
molnova catalog
related products
  • Phrixotoxin 3

    Potent blocker of voltage-gated sodium channels (IC50 values are 0.6, 42, and 72 nM for NaV1.2, NaV1.3 and NaV1.5 respectively). Blocks inward sodium currents in a voltage-dependent manner.

  • Dimethyl lithosperma...

    Dimethyl lithospermate B is a selective Na+ channel agonist.

  • Flecainide acetate

    A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart.